Abstract:The home-based working model triggered by COVID-19 has made it more challenging for women scientists to balance work and family life. In order to clarify the controversy of gender inequality in the field of scientific community, and to find out the causes and solutions of the issue, this study systematically reviews relevant international and domestic literature studies. It traces the characteristics and influencing factors of the marginalization of female scientists from a global perspective. The results show that the marginalization of female scientists is reflected in discipline development, citation markets, collaborative networks and career retention rates. Gender bias in science, gender perception in childhoodand adolescence,education systems and ideologies,gender temperament in science, and the image of scientists in the media are all factors that affect the status of female scientists. Guiding scientific interests in early education, active interventions in recruitment and career development, policy guarantees and support from women communities will be important ways to improve the unequal status for women scientists. Moreover, social media ushered in a new era of gender inclusion, which makes it a possible new way to combat sexism in science by images and hashtagson social media.