Abstract:UNESCO Recommendation on Open Science considers science communication as one of the pillars of open science and supports for science communication alongside open science practices. By analyzing the trends of scientific communication transformation under the leadership of Open Science, it can provide insights into building a more open, inclusive, and efficient scientific communication system. This paper uses literature research method and network research method to sort out the existing practice and theoretical research. Based on the 5W research perspectives of subject, audience, channel, content and effect, it is found that science communication under the leadership of open science, while science communication has made it possible to popularize and intellectualize communication subjects, to involve communication audiences, to open up communication channels, to enrich communication resources, and to make the effectiveness of communication more equitable, it also faces problems such as infringement, limited willingness of the public to participate, limited dissemination of platforms, crisis of confidence in the content, and unequal distribution of resources. There is a need to strengthen the protection of intellectual property rights, establish incentives for public participation, promote the optimization and upgrading of platforms, strengthen content quality control and achieve a balanced distribution of resources.